منابع مشابه
New allergy drug excipient allergy
Background Because of its rarity, drug excipients allergy is often unsuspected by the doctors. Some times the active drug is blamed and discontinued unnecessarily when the real culprit is drug excipients. This was suspected when patients reported exacerbation of urticaria with anti histaminic which are actually used for treating urticaria. After suspecting drug excipient as the cause of allergy.
متن کاملDrug allergy
Allergic drug reactions occur when a drug, usually a low molecular weight molecule, has the ability to stimulate an immune response. This can be done in one of two ways. The first is by binding covalently to a self-protein, to produce a haptenated molecule that can be processed and presented to the adaptive immune system to induce an immune response. Sometimes the drug itself cannot do this but...
متن کاملDrug allergy.
Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A thorough history is essential to the management of drug allergy. Laboratory testing has a very limited role in the management of drug allergy. Graded dose challenges and procedures to induce drug tolerance might be required in...
متن کاملInflammation and drug idiosyncrasy--is there a connection?
"Drug idiosyncrasy" refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of therapy. The liver is a frequent target for toxicity. Much of the conventional thinking about mechanisms of drug idiosyncrasy has centered on hypotheses that the reactions have a metabolic basis involving drug metabolism polymorphisms or th...
متن کاملDrug Allergy
Introduction Adverse reactions to pharmaceutical and diagnostic products constitute a major hazard in the practice of medicine and are responsible for substantial morbidity and cost. Adverse drug reactions can be divided into predictable and unpredictable reactions. Predictable reactions including drug toxicity, drug interactions, and adverse effects are dose dependent, can be related to known ...
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ژورنال
عنوان ژورنال: Journal of the American Medical Association
سال: 1919
ISSN: 0002-9955
DOI: 10.1001/jama.1919.02610360029008